NFL Week 10 Player Prop Bets: Best Odds & Picks This Week

We split our NFL player props last week and carry a winning record on the year into this week as we offer our NFL Week 10 player prop bets and odds.
We're focusing on four quarterbacks this week, including one of the NFL MVP odds favorites in a tricky spot against a division rival.
He's one of three players on our bet slip whose teams could boost their Super Bowl odds with a win - two of which we expect to help their side put up points on Sunday.
Here are my favorite player props for this weekend as part of our NFL Week 10 predictions.
NFL player prop bets for Week 10
NFL odds subject to change. Track the NFL scores for the latest line movement and matchup info.
- Bryce Young to throw an interception (-134 via BetRivers) vs. Giants ⭐⭐⭐⭐⭐
- Sam Darnold Over 1.5 passing TDs (-130 via bet365) at Jaguars ⭐⭐⭐⭐
- Patrick Mahomes Under 233.5 passing yards (-110 via bet365) vs. Broncos ⭐⭐⭐⭐
- Jalen Hurts to score an anytime touchdown (+100 via BetMGM) at Cowboys ⭐⭐⭐⭐⭐
NFL picks made Friday; odds subject to change. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!
Best NFL player prop bets this week
Bryce Young to throw an interception (-134) ⭐⭐⭐⭐⭐
This wager is the gift that keeps on giving for bettors who don't mind laying a little extra juice.
We've bet on a Young interception each of the last two weeks and cashed both times, as the sophomore QB continues to let it rip for a Panthers team that has very little to gain aside from Young's development.
To be fair, last week's interception came on one of the best throws of Young's career. But the fact that it still resulted in a turnover speaks to the level of talent around him, too, especially with Adam Thielen (hamstring) still on injured reserve.
Even if Young was a little unlucky with that throw, he also got away with a turnover-worthy play last week, per PFF, and had two more the week before.
Young has thrown at least one interception in all four of his starts this season, and if that happens again this week against the Giants, a $10 bet at BetRivers would return a $7.46 profit - 34 cents better than the price anywhere else.
Best odds: -134 via BetRivers | Implied probability: 57.26%
Sam Darnold Over 1.5 passing TDs (-130) ⭐⭐⭐⭐
At what point will our best NFL betting sites start to show a little respect to Darnold, who has consistently proven himself to be a worthwhile leader of this Vikings offense?
Through nine starts, Darnold has thrown for multiple touchdowns in six of them, including each of the last two games after he torched the Indianapolis Colts last week to the tune of 290 yards and three touchdowns.
He should be able to tee off this week against the Jacksonville Jaguars, who rank dead last in EPA/pass allowed (0.29) and have allowed multiple passing TDs in six of nine games after Jalen Hurts threw two touchdowns last week.
Darnold has cleared this total in 66.6% of his starts, and the Jaguars have surrendered the same in 66.6% of their games, yet these -130 odds from bet365 only carry an implied probability of 56.52%.
That's why I love the value here on this wager, which would turn a winning $10 ticket into a $7.69 profit.
Best odds: -130 via bet365 | Implied probability: 56.52%
Patrick Mahomes Under 233.5 passing yards (-110) ⭐⭐⭐⭐
Look, I think Mahomes has a legitimate case for MVP at the helm of the unbeaten Chiefs, largely because of his stellar play in critical situations on third down or late in the game.
That still hasn't lent itself to high yardage totals for the two-time MVP, who is averaging a career-low 242.8 passing yards per game with his second-lowest yards per attempt (7.2) and third-worst success rate (51.9%) as a starter.
Now he'll face off against the Broncos, who rank second in EPA/pass allowed (-0.18) even after Lamar Jackson - who has enjoyed heavy passing volume all season long - skewing that number with a dynamite performance last week.
I'd expect star cornerback Patrick Surtain and the rest of this defense to dial up a better game plan this week against a familiar foe in Kansas City, which clearly doesn't need to air it out to keep winning games by narrow margins.
This prop total is three yards higher than some of our best sportsbooks offer, while these -110 odds via bet365 are the best of the bunch.
Best odds: -110 via bet365 | Implied probability: 52.38%
Jalen Hurts to score an anytime touchdown (+100) ⭐⭐⭐⭐⭐
I included this bet in our weekly touchdown parlay (to be published soon), but it's also one of my favorite bets of the week across our best NFL prop betting sites.
Hurts has been a touchdown machine this season, scoring eight times in eight starts with a combined six scores over his last three weeks.
I fully expect that streak to continue against a horrid Dallas Cowboys defense that ranks dead last by virtually any metric against the run.
That should spell plenty of red-zone opportunities for Hurts, who has finished with double-digit carries in three of his last four games. If he scores once again, BetMGM will pay out $10 in profit for every $10 wager.
Best odds: +100 via BetMGM | Implied probability: 50%
NFL betting odds pages
Here are our best NFL betting sites:
- Caesars Promo Code: SBRBONUSDYW | Read our Caesars Review
- BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
- bet365 Bonus Code: SBRBONUS | Read our bet365 Review
- FanDuel Promo Code | Read our FanDuel Review
- DraftKings Promo Code | Read our DraftKings Review
(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.
Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
Related pages
- Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)