Sunday Night Football Odds & Picks Week 13: Updated SNF Betting Lines for Bills vs. 49ers
The Buffalo Bills enjoyed a bye following their biggest win of the 2024 NFL season and return to play as 6.5-point home favorites over the San Francisco 49ers by the Week 13 Sunday Night Football odds and betting lines.
The 9-2 Bills are favored by as much as 7 points by the NFL Week 13 odds at Highmark Stadium in Orchard Park, N.Y. with an 8:20 p.m. ET kickoff on NBC and Peacock.
Buffalo sits safely atop the AFC East standings following a 30-21 win over the Kansas City Chiefs two weeks ago. That victory seriously improved the Bills' Super Bowl odds and made QB Josh Allen the NFL MVP odds favorite.
The injury-ravaged 49ers lost 38-10 on the road to the Green Bay Packers this past week to slip to 5-6 and last in the NFC West. Mike Spector breaks down this week's matchup with his 49ers vs. Bills early picks.
Who's playing Sunday Night Football this week?
Here are some quick betting trends for the Week 13 Sunday Night Football matchup between the 49ers and Bills:
49ers vs. Bills (-6.5)
| 49ers | Bills | |
|---|---|---|
| Moneyline | 5-6 | 9-2 |
| ATS | 4-7 | 7-4 |
| Over/Under | 6-5 | 7-4 |
Sunday Night Football odds Week 13: 49ers vs. Bills
- Point spread: 49ers +7 (-110 via Caesars) | Bills -6.5 (-115 via BetMGM)
- Moneyline: 49ers +260 via bet365 | Bills -310 via DraftKings
- Over/Under: Over 46 (-110 via DraftKings) | Under 46.5 (-115 via FanDuel)
Stay up to date on the NFL's full primetime schedule with the Thursday Night Football odds and Monday Night Football odds.
Sunday Night Football 2024 betting results
| Week | Result | ATS | Total |
|---|---|---|---|
| Week 1 | Chiefs 27, Ravens 20 | Chiefs -2.5 | O45.5 |
| Week 1 | Lions 26, Rams 20 | Lions -5.5 | U53.5 |
| Week 2 | Texans 19, Bears 13 | Bears +6.5 | U45.5 |
| Week 3 | Chiefs 22, Falcons 17 | Chiefs -3.5 | U46.5 |
| Week 4 | Ravens 35, Bills 10 | Ravens -2.5 | U47.5 |
| Week 5 | Cowboys 20, Steelers 17 | Cowboys +2.5 | U44.5 |
| Week 6 | Bengals 17, Giants 7 | Bengals -4.5 | U45.5 |
| Week 7 | Steelers 37, Jets 15 | Steelers +2.5 | O40.5 |
| Week 8 | 49ers 30, Cowboys 24 | 49ers -5.5 | O47.5 |
| Week 9 | Vikings 21, Colts 13 | Vikings -5.5 | U46.5 |
| Week 10 | Lions 26, Texans 23 | Texans +4 | P49 |
| Week 11 | Chargers 34, Bengals 27 | Chargers -0.5 | O48.5 |
| Week 12 | Eagles 37, Rams 20 | Eagles -2.5 | O47.5 |
Don't miss our lists of the best NFL parlay betting sites and top NFL prop betting sites!
Sunday Night Football 2024-25 schedule & how to watch
| Week | Matchup | Time (ET) | TV |
|---|---|---|---|
| Week 13 | 49ers vs. Bills | 8:20 p.m. ET | NBC |
| Week 14 | Chargers vs. Chiefs | 8:20 p.m. ET | NBC |
| Week 15 | Packers vs. Seahawks | 8:20 p.m. ET | NBC |
| Week 16 | Texans vs. Chiefs | 1 p.m. ET | NBC |
| Week 16 | Buccaneers vs. Cowboys | 8:20 p.m. ET | NBC |
| Week 17 | Dolphins vs. Browns | 8:20 p.m. ET | NBC |
| Week 18 | TBD | TBD | NBC |
Sunday Night Football betting tips
Get an early start
The Sunday Night Football game is one of the most popular betting events of the week – which means plenty of action, and line movement to match. Start monitoring the lines and totals as soon as they become available; if they move in a favorable direction, you can wait. If you see movement away from your position, consider pulling the trigger earlier.
Embrace in-game betting
While you might struggle to find value in the most popular markets for any marquee prime-time NFL game, you're sure to unearth some worthwhile plays once the game starts. Live betting might not be your thing when there are a handful of games going on at the same time, but Sunday Night Football is the perfect time to lay into some live action via our best live betting sites.
Be wary of winter weather
Night games can get downright bone-chilling – and there are two games in particular that NFL bettors should monitor closely: Week 13's two tilts between the Dolphins and Packers at Lambeau Field, and the 49ers-Bills matchup at Highmark Stadium. Check out our guide on how to bet on the NFL for suggestions on how to approach betting on cold-weather games.
Check out our list of the best sportsbook promos here!
Sunday Night Football FAQs
Who will make the most Sunday Night Football appearances in 2024?
The Chiefs will appear on Sunday Night Football four times during the 2024-25 season, including Opening Night. The Houston Texans and Dallas Cowboys will appear in three such matchups.
Which team has the most SNF wins all-time?
Entering 2024, and including postseason Sunday Night Football games, the Cowboys have the most SNF victories all-time with 32 – four more than the Pittsburgh Steelers. Meanwhile, the Buffalo Bills have the highest Sunday Night Football win rate at 83.3% (10-2 SU).
Which teams have made the most and fewest Sunday Night Football appearances?
The Dallas Cowboys have been the most popular Sunday Night Football participant since NBC began broadcasting the games in 2006, with America's Team appearing in 60 SNF showdowns – 10 more than the second-place Steelers. Jacksonville enters 2024 having made just five SNF appearances.
NFL betting odds pages
Check out our best NFL betting sites:
- Caesars Promo Code: SBRBONUSDYW | Read our Caesars Review
- BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
- bet365 Bonus Code: SBRBONUS | Read our bet365 Review
- FanDuel Promo Code | Read our FanDuel Review
- DraftKings Promo Code| Read our DraftKings Review
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Related pages
- Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)
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