Women's March Madness Odds 2025: South Carolina Favorite to Repeat

With the 2024-25 college basketball season underway, there's an interesting battle near the top of oddsboard for the women's national title across our best March Madness betting sites.

The South Carolina Gamecocks may be the next dynasty in women's college basketball after knocking off Caitlin Clark and the Iowa Hawkeyes in last season's national championship game. With three titles to her name, head coach Dawn Staley's Gamecocks opened as the consensus favorite across our our best sports betting sites to win it all again in 2025.

• After winning last year's title, South Carolina (+160) opened as the clear favorite to repeat with the bulk of their championship-winning team set to return
• UConn (+400), always a threat under legendary head coach Geno Auriemma, retained superstar guard Paige Bueckers
• USC (+450) also has a superstar, with now-sophomore Juju Watkins considered by many to be the best player in the sport
• According to our best sports betting sites, Iowa (+20000) is extremely far from contending after WNBA Rookie of the Year Caitlin Clark made the jump to the WNBA

Here's a look at the latest 2025 Women's March Madness odds.

Women's March Madness odds 2025

Live Women's March Madness odds from out best sports betting apps.

Women's March Madness odds favorites 2025

South Carolina (+160)

South Carolina became the 10th undefeated champion in women's college basketball and the first since UConn in 2015-16 after beating Iowa 87-75 in the national championship.

Set to lose senior superstar and reigning SEC Defensive Player of the Year Kamilla Cardoso to the WNBA, the Gamecocks now have an opening in their frontcourt, but it shouldn't impact them too much.

Staley has a loaded roster, many of whom are returning from last year's championship-winning team. 

Eight of the nine players who played over 10 minutes per game last season are back, including guards Te-Hina Paopao and Raven Johnson. Sophomore phenom MiLaysia Fulwiley will likely take another step in her development, making the Gamecocks all the more dangerous.

Meanwhile, a lot is expected from fellow sophomore Tessa Johnson after she showcased her talent in the championship game with 19 points off the bench.

South Carolina faced a serious test in its season opener, only defeating Michigan by six, 68-62. It was Chloe Kitts, the clear Cardoso replacement, who dropped 19 points and 14 rebounds to secure the victory.

Between Staley's coaching ability and how she's built this roster as a master recruiter, it's no wonder the Gamecocks odds are already so short. The +160 odds imply a 38.46% probability South Carolina repeats, according to our odds calculator. 

Best odds: +160 via BetMGM | Implied Probability: 38.46%

UConn (+400)

With Bueckers returning for her redshirt senior season, the Huskies are the only team in the country with a former women's Wooden Award winner. As a freshman, Bueckers was voted the best player in the country, but injuries as a sophomore and junior derailed her development. She came back with a vengeance this past season averaging 21.9 points, 5.2 rebounds, and 3.8 assists while shooting 41.6% from deep.

As long as Bueckers is healthy, UConn is a threat to win its first national championship since 2016. While Geno Auriemma's program lost WNBA first-rounder Aaliyah Edwards, a plethora of young talented players are returning. Juniors Ashlynn Shade and KK Arnold headline the supporting cast in 2024-25, along with star freshman Sarah Strong.

Best odds: +400 via BetMGM | Implied Probability: 20%

USC (+450)

After falling to the Huskies as a No. 1 seed in last year's Elite Eight, the USC Trojans' odds to win it all in 2025 started a little bit longer than many were expecting.

Since then, they've dropped significantly to the third-shortest (+450). Trojans star JuJu Watkins is set to inherit the title of most prolific scorer in college basketball from Clark after averaging 27.1 as a freshman.

Head coach Lindsay Gottlieb has improved USC in each of her first three seasons at the helm and is expected to win the Pac-12 this upcoming season, especially with Stanford Cardinal star Cameron Brink heading to the WNBA. Watkins already looked like a future No. 1 pick as a freshman, so how good could she be with another year of development under her belt?

The early returns are quite something for Watkins - she dropped 27 points, 10 rebounds, four assists, three steals, and five blocks as the Trojans nearly defeated Ole Miss in their season opener.

Best odds: +450 via BetMGM | Implied Probability: 18.18%

2025 Women's March Madness odds over time

Past Women's March Madness winners

Women's March Madness FAQs

Who is the Women's March Madness favorite?

The South Carolina Gamecocks (+180) are the betting favorites across all of our best March Madness betting sites, with an implied win probability of 38.46%, according to our odds calculator. 

Who won Women's March Madness last year?

The South Carolina Gamecocks defeated the Iowa Hawkeyes, 87-75, in last year's national title game.

When does Women's March Madness 2025 start?

Selection Sunday will be on Sunday, March 16.

When will Women's March Madness be decided?

The 2025 national championship game will take place on Sunday, April 6.

Where will Women's March Madness be played?

The 2025 Final Four and National Championship Game will be held inside Amalie Arena in Tampa, Florida.

Here are our best March Madness betting sites:

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